How To Do Autophage Questline In No Man’s Sky?

To start the Autophage questline in No Man's Sky, follow these steps:

  1. Complete the Main Campaign: Finish "The Purge," the final quest in the Artemis main storyline.

  2. Create a Planetary Settlement & Complete 'A Trace of Metal': Establish a settlement and complete the "A Trace of Metal" quest, which involves creating a sentinel companion. Ensure there are no pending tasks for your settlement before proceeding.

  3. Visit a Dissonant Star System: Warp to a Dissonant Star System, identified by its corrupt planets. On the galaxy map, look for descriptions indicating such systems. Alternatively, for Switch players, perform approximately 25 warps until Iteration Tethys contacts you via the Space Anomaly.

After meeting these requirements, you should receive a distress call from a wounded Autophage when entering a suitable star system. Responding to this call initiates the first quest in the Autophage storyline titled "They Who Returned". Follow subsequent prompts within the game to progress through the questline.